Human serum is the acellular fluid remaining after blood serum clotting removes clotting factors, fibrinogen, and cellular components from human blood. What remains is a protein-rich matrix carrying growth factors, immunoglobulins, serum immunoglobulins, and transport proteins specific to human physiology.
Human blood plasma retains clotting factors that human serum does not. For cell culture applications where fibrinogen interference would compromise results, serum is the correct fraction. Culturing human cell lines in serum-supplemented media requires a preparation that supports human cell lines’ viability without introducing the coagulation activity that plasma-based supplements carry.
Human AB serum is collected from AB blood group donors, whose serum lacks anti-A and anti-B antibodies, making it the preferred format for cell therapy research and culturing human cell lines from donors across blood groups without agglutination risk. It is the closest human-origin alternative to fetal bovine serum for applications that prioritize physiological relevance over cost and convenience.
Equitech-Bio supplies human serum sourced from screened donors with documented lot data. Red blood cells and white blood cells are fully removed during processing, and blood cells carry no carryover into the final preparation. For downstream detection, human albumin serum and human body plasma extend human-origin reagent coverage across serum and plasma fraction applications. Research use only.
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