Normal cat serum is the acellular protein fraction of feline whole blood, isolated after clotting removes fibrinogen and cellular components. It carries species-specific antibodies, immunoglobulins, and transport proteins that reflect feline physiology. The biological context that non-matched sera cannot replicate in cat-model research.
Cat serum is supplied sterile, filtered, and preservative-free, as research use requires preservative-free material. The absence of preservatives maintains protein activity in sensitive downstream conjugate and detection applications. Each lot is documented for its current immunoglobulin content and processed to minimize hemolysis, since hemoglobin interference affects photometric assay readouts in ways that are difficult to correct after the fact.
For extended storage, aliquot on first use and avoid repeated freezing of working stock. Repeated freezing degrades antibodies and reduces blocking performance across subsequent uses. Centrifuge briefly after thawing if particulates are visible before applying to your protocol.
Sterile filtered horse serum offers a parallel large-animal serum option for comparative species work. For immunohistochemistry and ELISA workflows using rabbit-derived primaries alongside feline matrices, goat anti-rabbit polyclonal antibody detection reagents integrate cleanly into the same protocol design. Research use only.
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